Nembutal Pentobarbital Sodium HCL


Nembutal® Sodium Solution CII (pentobarbital sodium injection, USP)DESCRIPTION: 50 mg/mL Multi-dose Vial – SterileCOMPARE

Pentobarbital is used short-term to treat insomnia. Pentobarbital is also used as an emergency treatment for seizures, and to cause you to fall asleep for surgery.

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Nembutal Pentobarbital Sodium HCL CII (pentobarbital sodium HCL).

Pentobarbital is used short-term to treat insomnia. Nembutal Pentobarbital Sodium HCL is also used as an emergency treatment for seizures, and to cause you to fall asleep for surgery.

How should I take Nembutal (pentobarbital)?

Nembutal Pentobarbital Sodium is given as an injection into a muscle or vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

When injected into a vein, pentobarbital must be given slowly.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Do not stop using pentobarbital suddenly after using it long-term, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when you stop using pentobarbital.

To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any follow-up visits to your doctor.

If you store pentobarbital at home, keep it at room temperature away from moisture and heat.

Keep track of how much of this medicine has been used. Nembutal Pentobarbital Sodium is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?
Since Nembutal Pentobarbital Sodium is often used only when needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of pentobarbital can be fatal.

Overdose symptoms may include pinpoint or dilated pupils, weak or limp feeling, urinating less than usual or not at all, fast heart rate, slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

What should I avoid while taking Nembutal (pentobarbital)?
Pentobarbital can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. Alcohol can add to sleepiness caused by pentobarbital, which could be dangerous.

Nembutal Pentobarbital Sodium HCL side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

confusion, hallucinations;
weak or shallow breathing;
slow heart rate, weak pulse; or
feeling like you might pass out.
Less serious side effects may include:

problems with memory or concentration;
excitement, irritability, or aggression (especially in children or older adults);
loss of balance or coordination;
nausea, vomiting, constipation;
headache; or


STORAGE: Exposure of pharmaceutical products to heat should be minimized.Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at 20-25°C (68-77°F), however, brief excursions are permitted between 15-30°C (59-86°F).

Additional Information




Molecular weight



70–90% (oral); 90%

Biological half-life

15–48 hours










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